Table of Contents Cliend Education
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FiFi
Case A
| Signalment: 10-year-old
spayed female poodle, FiFi weighing 10 pounds |
Physical
Examination: 4/6 holosystolic murmur; mitral PMI, T = 100.2, P = 200, R = panting
Hydration appears normal. A moderate amount of dental tarter is present. |
 |
| History: Cough
and syncopal episodes with exercise, orthopnea. The signs have been present for 6 weeks. |
| Hematology |
Chemistries |
Urinalysis |
| WBC/uL |
8,200 |
BUN mg/dl |
20 |
Collection Method |
voided |
| WBC Corrected |
|
Creatinine mg/dl |
1.2 |
Color |
yellow |
| Mycete |
|
Glucose mg/dl |
98 |
Transparency |
clear |
| Meta |
|
ALT U/L |
85 |
Specific Gravity |
1.040 |
| Band |
|
CK U/L |
|
pH |
6 |
| Seg |
6,760 |
AP U/L |
40 |
Protein |
+1 |
| Lymph |
1,030 |
Cholesterol mg/dl |
300 |
Glucose |
|
| Mono |
410 |
T Protein g/dl |
7.3 |
Ketones |
|
| Eos |
|
Albumin g/dl |
3 |
Bilirubin |
|
| Baso |
|
Globulin g/dl |
4.3 |
Hemoglobin |
|
| NRBC/100 WBC |
|
Calcium mg/dl |
10 |
RBC/HPF |
|
| RBC Morphology |
normal |
Phosphorus mg/dl |
3.8 |
WBC/HPF |
3-5/HPF |
| RBC/uL x 106 |
7 |
Sodium mEq/L |
140 |
Casts/LPF |
|
| Hgb g/dl |
16 |
Potassium mEq/L |
3.8 |
Epithelial cells/HPF |
|
| PCV % |
48 |
Chloride mEq/L |
102 |
Crystals/HPF |
|
| T Protein g/dl |
|
|
|
|
|
| Fibrinogen mg/dl |
|
|
|
|
|
| Reticulocytes |
|
|
|
|
|
| Platelets/uL |
adequate |
|
|
|
|
Thoracic and abdominal radiographs disclosed
- generalized cardiac enlargement and left atrial enlargement
resulting in elevation of the left mainstem bronchus
- mild pulmonary edema
- hepatomegaly
List Fifi's problems identified from history, physical exam
and radiographs. Discuss the significance of the problems.
FiFi was treated with the following medications. Please
look up in a cardiology text what each of these drugs does.
- Digoxin
- Lasix (furosemide)
- Captopril
4 days later she is vomiting, anorexic, has diarrhea, is
weak, and atrial premature contractions (APC) are observed on electrocardiogram.

Lab tests, 4 days after beginning treatment:
| Hematology |
Chemistries |
Urinalysis |
| WBC/uL |
10,000 |
BUN mg/dl |
80 |
Collection Method |
cystocentesis |
| WBC Corrected |
|
Creatinine mg/dl |
3.1 |
Color |
light yellow |
| Mycete |
|
Glucose mg/dl |
100 |
Transparency |
clear |
| Meta |
|
ALT U/L |
100 |
Specific Gravity |
1.017 |
| Band |
|
CK U/L |
|
pH |
5 |
| Seg |
9,200 |
AP U/L |
40 |
Protein |
+1 |
| Lymph |
800 |
Cholesterol mg/dl |
290 |
Glucose |
|
| Mono |
|
T Protein g/dl |
8.6 |
Ketones |
|
| Eos |
|
Albumin g/dl |
4.2 |
Bilirubin |
|
| Baso |
|
Globulin g/dl |
4.4 |
Hemoglobin |
|
| NRBC/100 WBC |
|
Calcium mg/dl |
11.6 |
RBC/HPF |
3-5 |
| RBC Morphology |
normal |
Phosphorus mg/dl |
6 |
WBC/HPF |
0-1 |
| RBC/uL x 106 |
7.7 |
Sodium mEq/L |
145 |
Casts/LPF |
|
| Hgb g/dl |
20 |
Potassium mEq/L |
2 |
Epithelial cells/HPF |
|
| PCV % |
55 |
Chloride mEq/L |
99 |
Crystals/HPF |
|
| T Protein g/dl |
|
|
|
Other |
|
| Fibrinogen mg/dl |
|
|
|
|
|
| Reticulocytes |
|
|
|
|
|
| Platelets/uL |
adequate |
|
|
|
|
What happened to FiFi to explain the clinical signs and
changes in laboratory parameters after treatment?
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College of Veterinary Medicine,
Washington State University, Pullman, WA,
99164-7010 USA
Copyright Washington State University
Revised July 26, 2007
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